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[DOI] [PMC free article] [PubMed] [Google Scholar] 117.Mayes S., Calhoun S.L., Aggarwal R., Baker C., Mathapati S., Molitoris S., Mayes R.D

The binding of ammonium to TNF- activates its death domain, recruits TRADD (Tumor Necrosis factor receptor-associated death domain protein) and FADD (Fas-associating protein with a novel death domain) proteins, forms a complex, activates Caspase-8, and subsequently Caspase-3, leading to apoptosis (147)